Glioblastoma Multiforme
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 For People with Newly Diagnosed Glioblastoma Multiforme
NovoCure Trial

The NovoTTF is a portable, investigational device for cancer treatment using Tumor Treating Fields. The device is used in addition to the standard treatments.

Trials and Noteworthy Treatments

  Treatment Next 25 Location Last Updated
Details A Phase 1b Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Gliomas San Antonio, TX 01/24/2010
Details A Phase 2a Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Glioma Duarte, CA
Chicago, IL
Columbus, OH
San Antonio, TX 		01/24/2010
Details Anti-Tumor Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed Glioblastoma Multiforme During Recovery From Therapeutic Temozolomide-induced Lymphopenia Durham, NC 01/24/2010
Details Evaluation of Recovery From Drug-Induced Lymphopenia Using Cytomegalovirus-Specific T-Cell Adoptive Transfer [ERaDICATe] Durham, NC 01/24/2010
Details Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma Los Angeles, CA 01/24/2010
Details Phase I Study of Glioma-Associated Antigen (GAA) Peptide-Pulsed Dendritic Cell Vaccination in Malignant Glioma Patients Los Angeles, CA 01/24/2010
Details Phase I/II Study of GP96 Heat Shock Protein-Peptide Complex Vaccine in Patients With Recurrent or Progressive High-Grade Glioma San Francisco, CA 01/24/2010
Details PHASE II, Single-arm, Open-label Investigation of HSPPC-96 Vaccine With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme San Francisco, CA 01/24/2010
Details Phase ll Trial of Tumor Lysate-Pulsed Dendritic Cell Immunotherapy for Patients With Atypical or Malignant, Primary or Metastatic Brain Tumors of the Central Nervous System Los Angeles, CA 01/24/2010
Details Prospective, Phase II Clinical Trial to Evaluate Efficacy and Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme Patients After Complete Surgical Resection With Fluorescence Microscope Pamplona, SPAIN 01/24/2010
Details Vaccine Therapy in Treating Patients Undergoing Surgery for Recurrent Glioblastoma Multiforme Durham, NC 01/24/2010
Details Phase I Dose Escalation Study of Autologous Antigen-Pulsed Dendritic Cell Immunotherapy for Malignant Gliomas (e.g. Glioblastoma Multiforme, Anaplastic Astrocytoma) Los Angeles, CA
Los Angeles, CA 		01/24/2010
Details Phase I Study of Intratumoral and/or Resection Cavity Administration of Recombinant Measles Virus Encoding Human Carcinoembryonic Antigen in Patients With Recurrent Glioblastoma Multiforme Rochester, MN 01/24/2010
Details Phase II Study of CDX-110 in Patients With Glioblastoma Multiforme (GBM) (ACT III) Los Angeles, CA
Los Angeles, CA
Orange, CA
Palo Alto, CA
San Francisco, CA
New Haven, CT
Gainsville, FL
Jacksonville, FL
Atlanta, GA
Iowa City, IA
Chicago, IL
Chicago, IL
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Cleveland, OH
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Charlottesville, VA
Seattle, WA 		01/24/2010
Details A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma Charleston, SC 01/14/2010
Details Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas Bourgogne, France 01/14/2010
Details A Phase II study of Bevacizumab (Avastin) plus Temodar and Tarceva during and after Radiation Therapy in patients with newly diagnosed Glioblastoma or Gliosarcoma San Francisco, CA 01/11/2010
Details ABTC 04-03: A Phase I Study of Vorinostat (Suberolyanilide Hydroxamic Acid [SAHA]) in Combination with Temozolomide in Patients with Malignant Gliomas San Francisco, CA 01/11/2010
Details ABTC05-02 - Phase I/II Studies of BAY 43-9006 (sorafenib) in Combination with OSI-774 (erlotinib), R115777 (tipifarnib) or CCI-779 (temsirolimus) in Patients with Recurrent Glioblastoma Multiforme or Gliosarcoma. San Francisco, CA 01/11/2010
Details Phase II Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Spectroscopy for Target Definition in Patients with Recurrent Glioma San Francisco, CA 01/11/2010
Details Phase II Trial of Dasatinib in Patient with Recurrent Glioblastoma Multiforme Cincinnati, OH 01/07/2010
Details A Study of Bevacizumab (Avastin) Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas Cincinnati, OH 01/03/2010
Details A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma Charleston, SC 12/30/2009
Details A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM) Hershey, PA 12/30/2009
Details A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma Philadelphia, PA 12/30/2009

News Stories

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Frequently Asked Questions



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  (0.7967)   What is your opinion on Dr Burzynskis antineoplaston therapy for brain tumors?

  (0.7967)   How do you get a brain tumor? What can you do to treat a brain tumor? Can you prevent a brain tumor? Will it ever just go away by itself? Why do you go into a coma? How long are you in a coma before you die? What percent of Americans have brain tumors? Is it likely since my great grandmother had a brain tumor that I will?

  (0.7967)   My husband was diagnosed with Glioblastoma Multiforme about 4 months ago. He has had surgery, radiation and chemotherapy; right now we are waiting to have an MRI done. He had his last treatment in August. What is next? What can I expect from here? Are there any new treatments or research available?

  (0.7967)   My sister-in-law just had surgery to remove a tumor identified as glioblastoma multiforme. The tumor was the size of a lemon. The doctor says that if it recurs, she is not a candidate for another surgery. How likely is ? What are the chances of complete recovery?

  (0.7967)   Having reviewed some statistical information, I still want to know: how many GBMs are diagnosed say, in a year, or by state, or by country. If, on average, a neurosurgeon only treats one per year, they canno be THAT common, can they?

  (0.7742)   My mother has been diagnosed with Glioblastoma Multiforme, tumor location: brain stem. She had a stereotactic biopsy and the doctor prescribed 40 radiation treatments with daily intake of Temodal 140mg. The radiation treatment clinic doesn~t work on weekends, so she goes 5 weekdays and pauses for 2 day week-end. However, the doctor told her to take Temodal even for week-ends till the rest of radiation treatment. That means that she would end up taking Temodal for 56 days! On the information sheet for Temodal, it is stated that Temodal should be taken for 42, up to 49 days max! Could you please tell me is it safe for my mother to take Temodal longer then 49 days? Is it safe to follow our doctor~s orders in continuing with Temodal until the end of 40 week-day radiation treatment (and end up taking Temodal for 56 days)? Should she continue taking Temodal on week-ends when she doesn~t go for radiation treatment?

  (0.7742)   My friend was diagonized in early May, 2004, with Glioblastoma Multiforme. He had surgery, radiation, and chemotherapy. After radiation, they did an MRI and it showed a new growth so he started the chemotherapy and, after four chemo treatments, they did another MRI and it had gotten bigger. They now want to do another surgery and try a different chemo. Are there any significant things we should worry about with the second surgery and, since it is still growing after radiation and chemotherapy, what are his chances of survival and how long?

  (0.7742)   What is the difference between diffuse astrocytoma grade three, a GBM, and AA grade three? Is it common for low white counts and low platelet counts to continually delay temodar treatments by a couple of weeks?

  (0.7742)   My 57-year-old brother has Glioblastoma Multiforme. He is on steroids and has been since Oct. Within the last five weeks, he has been bruising easily/bleeding on his lower arms and wrists. Does anyone know how this can be prevented? All he is done thus far is cover his lower arms with gauze! If someone could get back to me before 4:00 p.m. today, it would be greatly appreciated! Also, as long as we are on the subject, does anyone know of a doctor in New Jersey that is willing to work "outside the box" and supplement chemotherapy with additives, such as verapimil, tamoxifen, etc.?

  (0.7742)   My father was diagnosed with Glioblastoma Multiforme in mid-December 2003. The tumor is located in the left frontoparietal area and was thus deemed inoperable. He is about to begin the sixth and final week of radiation. He has also gone through his first round of chemotherapy (Temodar). During the course of his treatment, he has been going to work daily. Over the course of the last five weeks, his right side mobility had improved substantially and his radio-oncologist expressed cautious optimism regarding his prognosis. However, just as he is to begin his sixth week of radiation, he lost his balance twice and fell, and has lost some of the movement in his right arm. My question is: what can cause such deterioration of his neurological condition? Can it be explained by exhaustion, a side-effect of the treatment, or that the treatment has not halted the tumor's growth?

  (0.7742)   My father has just been diagnosed with Glioblastoma Multiforme. He is starting radiation tomorrow. I want to get him on some nutritional supplements to help out with energy, weight loss, hair loss, etc. I have some specific products from a company for which I am an Independent Distributor. Some of the products do have herbs in them. My first question is: my sister's concern that some herbs will make the tumor grow more. Have you ever heard of anything to this effect? Then secondly, I am under the impression that antioxidants are not absorbed when going through radiation treatment. Is this correct or does it hinder the radiation treatment in any way? I ask because the multivitamin I would like him to take does have antioxidants in it. Maybe I should be asking a nutritionist this. Any thoughts on this?




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