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A Phase II/III Randomized Study of CDX-110 With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme |
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Durham, NC USA |
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05/09/2008 |
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Phase 2, 2-Part, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of CT-322 Monotherapy and Combination Therapy With Irinotecan in Patients With Recurrent Glioblastoma Multiforme |
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Durham, NC USA |
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04/27/2008 |
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Phase I and II, Open-Label, Multi-Center Trials of Pazopanib in Combination with Lapatinib in Adult Patients with Relapsed Malignant Glioma |
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Durham, NC USA |
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04/15/2008 |
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Phase I/II Studies of BAY 43-9006 (Sorafenib) in Combination With OSI-774 (Erlotinib), R115777 (Tipifarnib) or CCI-779 (Temsirolimus) in Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma |
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Durham, NC USA |
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04/15/2008 |
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Phase II Single Arm Trial of VEGF Trap in Patients With Recurrent Temozolomide-Resistant Malignant Gliomas |
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Durham, NC USA |
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04/15/2008 |
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A Phase I Study of Vorinostat [Suberoylanilide Hydroxamic Acid (SAHA)] in Combination with Temozolomide in Patients with Malignant Gliomas |
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Durham, NC USA |
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04/15/2008 |
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Phase III Trial Comparing Conventional Adjuvant Temozolomide with Dose-intensive Temozolomide in Patients with Newly Dignosed Glioblastoma |
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Goldsboro, NC USA |
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04/11/2008 |
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Chemotherapy, Radiation Therapy, and Vaccine Therapy With or Without Daclizumab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery |
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Durham, NC USA |
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03/02/2008 |
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Evaluation of Recovery From Drug-Induced Lymphopenia Using Cytomegalovirus-Specific T-Cell Adoptive Transfer [ERaDICATe] |
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Durham, NC USA |
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03/02/2008 |
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NTI 0501: An Open-Labeled, Extended-Use of Human Corticotropin-Releasing Factor (hCRF) (Xerecept) Intended for Patients Who Participate in Dexamethasone-Sparing Studies NTI 0302 or NTI 0303 |
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Winston-Salem, NC USA |
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03/01/2008 |
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NABTC 04-01: Lapatinib in Treating Patients Who Are Undergoing Surgery for Recurrent Progressive Glioblastoma Multiforme or Gliosarcoma |
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Durham, NC USA |
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10/03/2007 |
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NABTC 04-02: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma
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Durham, NC USA |
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10/03/2007 |
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Phase I Dose Escalation of Gleevec in Combination With PTK787/ZK 222584 (PTK/ZK) Plus Hydroxyurea |
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Durham, NC USA |
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08/26/2007 |
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A Phase II Trial of Erlotinib (OSI-774) and Sorafenib (BAY 43-9006) for Patients With Progression or Recurrent Glioblastoma Multiforme |
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Winston-Salem, NC USA |
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08/26/2007 |
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Dynamic Contrast-Enhanced Magnetic Resonance Imaging With Bevacizumab (Avastin) in Combination With Irinotecan (CPT-11) for Malignant Gliomas |
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Durham, NC USA |
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08/26/2007 |
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A Phase I Study of Imatinib Mesylate (Gleevec) in Combination With Temozolomide (Temodar) in Patients With Malignant Glioma |
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Durham, NC USA |
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08/20/2007 |
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A Pilot Multicenter Phase I/II Trial of RAD001 in Patients With Recurrent Glioblastoma Multiforme |
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Durham, NC USA |
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08/19/2007 |
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A Single-Center, Open-Label, Phase II, Safety and Efficacy Study of Panzem Nanocrystal Colloidal Dispersion Administered Orally in Combination With Protracted Oral Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme |
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Durham, NC USA |
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08/19/2007 |
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Phase II trial of Gliadel plus O6-Benzylguanine for patients with recurrent glioblastoma multiforme. |
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Durham, NC USA |
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08/19/2007 |
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Phase I study of Gefitinib plus Rapamycin for patients with recurrent malignant glioma. |
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Durham, NC USA |
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08/18/2007 |
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Phase II treatments with Temodar® for adults with progressive,resistant or recurrent meningioma. |
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Durham, NC USA |
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08/18/2007 |
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A Phase II Open-Label, Multiple-Dose Study of Intracavitary Administered 131I-TM-601 in Adult Patients with Recurrent High-Grade Glioma |
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Charlotte, NC USA |
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08/18/2007 |
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Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor |
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Charlotte, NC USA |
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08/18/2007 |
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A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel® in Subjects With Recurrent Glioma |
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Chapel Hill, NC USA |
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08/18/2007 |
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A Phase II Study of Bevacizumab (Avastin) in Combination With Metronomic Temozolomide (Temodar)for Recurrent Malignant Glioma |
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Durham, NC USA |
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08/18/2007 |
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Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors |
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Winston-Salem, NC USA |
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08/18/2007 |
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Phase I and II, Open-Label, Multi-Center Trials of Pazopanib in Combination With Lapatinib in Adult Patients With Relapsed Malignant Glioma |
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Durham, NC USA |
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05/01/2007 |
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Phase I/II Study of Intravenous Infusion of Tetra-o-Methyl Nordihydroguaiaretic Acid (EM-1421) in Subjects With Recurrent High Grade Glioma |
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Winston-Salem, NC USA |
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05/01/2007 |
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Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma
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Winston-Salem, NC USA |
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05/01/2007 |
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A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High-Risk Low-Grade Gliomas |
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Goldsboro, NC USA |
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05/01/2007 |
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Cilengitide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme |
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Winston-Salem, NC USA |
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05/01/2007 |
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Phase II Study of Brachytherapy Using the Intracavity GliaSite® Radiation Therapy System (RTS) With or Without Stereotactic Radiosurgery in Patients With Newly Diagnosed Supratentorial Brain Metastases |
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Chapel Hill, NC USA |
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05/01/2007 |
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Talampanel, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
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Winston-Salem, NC USA |
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04/29/2007 |
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Phase II Trial of Talampanel in Conjunction With Radiation Therapy With Recurrent and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme |
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Winston-Salem, NC USA |
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04/29/2007 |
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A Feasibility Assessment and a Phase I/II Trial of MLN518 (Tandutinib) for Treatment of Patients with Recurrent Glioblastoma |
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Winston-Salem, NC USA |
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04/28/2007 |
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Comprehensive Genetic Analysis Of Brain Tumors In Children. (A Non-Therapeutic Study) |
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Winston-Salem, NC USA |
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10/12/2006 |
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Comprehensive Genetic Analysis Of Brain Tumors In Children. (A Non-Therapeutic Study) |
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Charlotte, NC USA |
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10/12/2006 |
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Comprehensive Genetic Analysis Of Brain Tumors In Children. (A Non-Therapeutic Study) |
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Chapel Hill, NC USA |
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10/12/2006 |
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Phase I/II Study of Topotecan, Filgrastim (G-CSF), and Radiotherapy in Young Patients With Newly Diagnosed Malignant Intrinsic Pontine Brain Stem Glioma |
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Charlotte, NC USA |
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05/30/2006 |
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Phase II Study of Rituximab, Temozolomide, and Methylprednisolone in Patients With Recurrent Primary CNS Non-Hodgkin`s Lymphoma |
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Durham, NC USA |
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05/27/2006 |
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Phase 3 study: Radiation Therapy and Combination Chemotherapy Followed by Autologous Stem Cell Transplant in Treating Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor |
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Durham, NC USA |
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05/02/2006 |
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Phase II Study of O6-Benzylguanine and Temozolomide (Temodar) in Pediatric Patients With Recurrent or Progressive High-Grade Gliomas or Brain Stem Tumors |
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Durham, NC USA |
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05/01/2006 |
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Phase II Study of O6-Benzylguanine and Temozolomide (Temodar) in Pediatric Patients With Recurrent or Progressive High-Grade Gliomas or Brain Stem Tumors |
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Durham, NC USA |
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05/01/2006 |
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A Pilot Study of Dronabinol for the treatment of nausea,vomiting and appetite loss in Adult Patients With Primary Gliomas |
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Durham, NC USA |
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05/01/2006 |
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Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors |
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Durham, NC USA |
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12/04/2005 |
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Phase I trial of Temozolomide (Temodar) and O6-Benzylguanine (o6-bg)in pediatric patients with recurrent brain tumors. |
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Durham, NC USA |
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12/03/2005 |
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Pharmacological intervention for learning impaired children surviving treatment for cancer. |
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Durham, NC USA |
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12/03/2005 |
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Quality of Life Studies (There are 19 seperate studies listed here) |
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Durham, NC USA |
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12/03/2005 |
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Phase I Dose Escalation Study of Gliadel in Adults with Recurrent Malignant Gliomas |
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Winston-Salem, NC USA |
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12/03/2005 |
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Phase I trial of Temodar plus O6-Benzylguanine plus Irinotecan (CPT-11) in the treatment of patients with recurrent/progressive Cerebral anaplastic gliomas. |
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Durham, NC USA |
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12/03/2005 |
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Phase II trial of Temodar ® plus O6-Benzylguanine in the treatment of patients with Temodar® -resistant malignant glioma.
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Durham, NC USA |
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12/03/2005 |
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Pilot study of systemic and intrathecal chemotherapy followed by conformal radiation for infants with embryonal intracranial central nervous system tumors. |
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Durham, NC USA |
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12/03/2005 |
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Phase II, multicenter, open-label trial of the safety and efficacy of Tarceva in patients with first relapse of grade IV glioma (glioblastoma multiforme) |
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Durham, NC USA |
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11/27/2005 |
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Phase II, multicenter, open-label trial of the safety and efficacy of Tarceva in patients with first relapse of grade IV glioma (glioblastoma multiforme) |
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Chapel Hill, NC USA |
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11/27/2005 |
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Pilot Study of Systemic and Intrathecal Chemotherapy Followed by Conformal Radiation for Infants with Brain Tumors |
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Durham, NC USA |
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11/27/2005 |
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Temozolomide in Treating Patients With Progressive Low-Grade Glioma
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Durham, NC USA |
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11/27/2005 |
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Details |
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Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas |
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Durham, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Durham, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Charlotte, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Winston Salem, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Greenville, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Chapel Hill, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Asheville, NC USA |
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11/27/2005 |
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Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma |
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Charlotte, NC USA |
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11/27/2005 |
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A Phase I, Molecular Biology, and Phase II Study of Lapatinib (GW572016) in Pediatric Patients with Recurrent or Refractory Medulloblastoma, Malignant Glioma or Ependymoma
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Durham, NC USA |
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11/27/2005 |
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Tipifarnib and Radiation Therapy in Treating Young Patients with Brainstem Glioma |
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Durham, NC USA |
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11/27/2005 |
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Details |
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Reliable Imaging Diagnosis of Recurrent Brain Tumor |
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Winston-Salem, NC USA |
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11/26/2005 |
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Bio-Anatomic Radiation Treatment Planning for Newly Diagnosed
Glioblastoma multiforme |
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Winston-Salem, NC USA |
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11/26/2005 |
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Conventional Radiation Therapy + Thalidomide for Supratentorial Glioblastoma |
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Winston-Salem, NC USA |
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11/26/2005 |
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Dose Escalation Study of RT Using 3-Dimensional Treatment Planning for Newly Diagnosed GBM |
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Winston-Salem, NC USA |
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11/26/2005 |
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Phase II Study of Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiotherapy With or Without Peripheral Blood Stem Cell Rescue in Patients With Intracranial Non-Germinomatous Germ Cell Tumors
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Charlotte, NC USA |
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11/26/2005 |
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Phase II Study of Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiotherapy With or Without Peripheral Blood Stem Cell Rescue in Patients With Intracranial Non-Germinomatous Germ Cell Tumors
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Charlotte, NC USA |
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11/26/2005 |
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Phase I Brachytherapy Dose Escalating Study Using the Proxima Therapeutics, Inc. GliaSIte RTS in Patients with Recurrrent Malignant Gliomas |
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Winston-Salem, NC USA |
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11/20/2005 |
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Phase II treatment with Irinotecan (CPT-11) plus Celebrex® of adults with primary malignant glioma. |
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Durham, NC USA |
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11/20/2005 |
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Phase II treatment with Temodar for patients with newly diagnosed, progressive or recurrent primary central nervous system lymphoma. |
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Durham, NC USA |
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11/20/2005 |
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Phase I/II trial of Temodar and escalating doses of Oral VP-16 for patients with recurrent malignant gliomas. |
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Durham, NC USA |
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11/20/2005 |
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Phase III randomized trial of the role of Whole Brain Radiation Therapy in addition to Radiosurgery in the management of patients with one to three cerebral metastases. |
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Durham, NC USA |
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11/13/2005 |
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Pilot trial of Innohep (Tinzaparin) Low Molecular Weight Heparin for primary prophylaxis of venous thromboembolism in brain tumor patients. |
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Durham, NC USA |
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11/13/2005 |
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Phase II study of VNP40101M for the treatment of adults with newly diagnosed or recurrent malignant glioma. |
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Durham, NC USA |
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11/13/2005 |
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Details |
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Phase II trial of Gleevec plus hydroxyurea in the treatment of patients with malignant glioma |
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Durham, NC USA |
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11/13/2005 |
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Details |
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Phase I, open-label, 2-arm dose escalation study of Imatinib Mesylate (Gleevec) in combination with Temozolomide (Temodar)in patients with glioblastoma multiforme and gliosarcoma. |
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Durham, NC USA |
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11/13/2005 |
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Phase I trial of Oral Topotecan plus Temodar in the treatment of patients with recurrent/progressive malignant gliomas. |
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Durham, NC USA |
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11/13/2005 |
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Pilot study of Irinotecan (CPT-11) given concurrently with 76 Gy of conformal multiple fraction per day External Beam Radiotherapy followed by Maintenance Therapy with BCNU plus Irinotecan (CPT-11) for newly diagnosed diffuse pontine glioma. |
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Durham, NC USA |
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11/13/2005 |
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Phase I treatment with Irinotecan (CPT-11) plus Temozolomide (Temodar) of children with primary recurrent malignant brain tumors. |
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Durham, NC USA |
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11/13/2005 |
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Pilot study of genetic and environmental Risk and outcome for newly diagnosed brain tumor patients and controls. |
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Durham, NC USA |
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11/13/2005 |
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Activation of A Pilot Comparison Bioavailability Study of Oral and Intravenously Administered Temozolomide (Temodar) in patients with primary CNS malignancies. |
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Durham, NC USA |
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11/13/2005 |
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Details |
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Phase I/II trial of ZD1839 (Iressa) in pediatric patients newly diagnosed with brain stem tumors or incompletely resected supratentorial malignant gliomas. |
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Durham, NC USA |
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11/13/2005 |
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Details |
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FR901228 in Treating Patients With Recurrent High-Grade Gliomas |
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Durham, NC USA |
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11/13/2005 |
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Details |
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VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors |
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Durham, NC USA |
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11/11/2005 |
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Phase II study of Oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors and atypical teratoid rhabodoid tumors. |
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Durham, NC USA |
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11/09/2005 |
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Details |
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Phase I, Gliadel® & Escalating Doses of Intravenous O6-Benzylguanine in People with Recurrent Malignant Glioma
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Winston-Salem, NC USA |
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11/09/2005 |
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Phase I/II, two-arm, multicenter, dose escalation study of Oral AEE788 administered on a continuous once daily dosing schedule in adult patients with recurrent or relapsing glioblastoma. |
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Durham, NC USA |
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11/07/2005 |
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Phase I study of Cilengitide in children with refractory brain tumors. |
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Durham, NC USA |
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11/06/2005 |
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Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases
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Chapel Hill, NC USA |
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11/06/2005 |
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Details |
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Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases |
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Winston-Salem, NC USA |
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11/06/2005 |
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Details |
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Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases |
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Goldsboro, NC USA |
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11/06/2005 |
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