Details For Selected Brain Tumor Treatment

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		Treatment Name:		Talampanel, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

		Phase:		Phase 2

		Treatment ID#:		1483 NCT00082992

		Age Group:		Adults Only

		Min Karnofsky Score:		60: Requires occasional assistance but is able to care for most of own needs

		Conditions:		Prior Surgery is Allowed Prior Radiation is Not Allowed Prior Chemotherapy is Not Allowed

		Last Updated:		04/29/2007

		Tumor Types:		Glioblastoma Multiforme


		Comments:		Induction therapy: Patients undergo radiotherapy once daily on days 1-5. Beginning on day 1 of radiotherapy, patients receive oral talampanel 3 times daily on days 1-7. Treatment repeats weekly for 6 weeks. Maintenance therapy: Beginning immediately after the completion of induction therapy, patients receive oral talampanel 3 times daily on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients are followed every 2 months.

		Treatment Type:		Chemotherapy Radiation

		Contact:		James Markert M.D. Associate Professor of Neurosurgery University of Alabama at Birmingham Comprehensive Cancer Center Comprehensive Cancer Center Birmingham, AL 35294 USA Phone: 205-975-3251 Fax: 205-975-3203 E-mail: kpowell@uabmc.edu Website:

Last updated refers to the date when our listing for each treatment was last updated.
ID is a combination of our internal ID and the official ID for the trial, if any.
Min Karnofsky is a general guide to how well you have to function to use this treatment

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