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Treatment Name: |
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Phase I/II Trial of Imatinib Mesylate; (Gleevec; ST1571) in Treatment of Recurrent Oligodendroglioma and Mixed Oligoastrocytoma |
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Phase: |
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Phase 1/2 |
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Treatment ID#: |
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1624 11500 |
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Age Group: |
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Adults Only |
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Min Karnofsky Score: |
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60: Requires occasional assistance but is able to care for most of own needs |
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Conditions: |
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Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Sometimes Allowed Histologically confirmed oligodendroglioma or mixed oligoastrocytoma
Grade 2-4
Recurrent disease
Failed prior surgery, radiotherapy, nitrosourea-based therapy, or temozolomide chemotherapy regimen
Progressive disease by MRI or CT scan
No more than 2 prior chemotherapy regimens
No prior or concurrent significant intratumoral hemorrhage |
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Last Updated: |
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06/26/2006 |
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Tumor Types: |
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Mixed Glioma Oligodendroglioma High Grade Oligodendroglioma Low Grade |
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Comments: |
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No prior interstitial chemotherapy, including carmustine wafers, unless separate lesion seen on MRI outside of prior treatment field |
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Treatment Type: |
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Chemotherapy |
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Contact: |
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Toni Kay Mangskau-MN Clinical Trials Referral Coordinator Mayo Clinic Cancer Center - MN 200 First Street SW Rochester, MN 55905 USA Phone: (507)538-7623 Fax: E-mail: mangskau.toni@mayo.edu Website: www.mayoclinic.org/cancer-treatment/ |
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