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Treatment Name: Phase I/II trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine For Patients With Recurrent High Grade Glioma
Keywords: Vaccine; Heat Shock
Phase: Phase 1/2
Treatment ID#s: VT1662        
Age Group: Adults Only
Min Karnofsky Score: 60: Requires occasional assistance but is able to care for most of own needs
Conditions: Newly Diagnosed: Y
Recurrent: Y
Prior Surgery is Allowed
Prior Radiation is Allowed
Prior Chemotherapy is Allowed
Patients must have a surgically accessible tumor for which surgical resection is indicated. Primary glioma patients are eligible for vaccine preparation and potential treatment at the time of tumor progression; recurrent glioma patients are eligible for vaccine preparation and treatment post-operatively. Patients may or may not have had prior chemotherapy, but must have been treated with radiotherapy. Patients may have had treatment for no more than 2 prior relapses, where `relapse` is defined as progression following initial therapy.
Last Updated: 10/03/2007
Tumor Types: Anaplastic Astrocytoma
Glioblastoma Multiforme
Gliosarcoma
Mixed Glioma
Comments: Treatment Plan: Patient undergoes standard surgical resection of tumor, tissue is immediately shipped overnight to Antigenics, Antigenics constructs the vaccine. Once the vaccine is constructed it is transported to the clinic and administered to the patient regularly according to a dosing schedule.
Treatment Type: Immunological, Biological or Targeted Therapy.
Contact: U. Of California At San Francisco
Michael Prados, MD
Professor
Contact: Dr. Michael Prados
400 Parnassus Avenue, Rm A808
San Francisco, CA 94143-
Phone:(415)353-2966
Fax: (415)353-2167
Click here to send an email
Website: neurosurgery.medschool.ucsf.edu/index.html



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