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  • Last updated refers to the date when our listing for each treatment was last updated.
  • ID is our internal ID - starting with VT.
  • Min Karnofsky is a general guide to how well you have to function to use this treatment
  • For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.
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Treatment Name: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma
Keywords: ANG1005
Phase: Phase 1
Treatment ID#s: VT1871         NCT00539344
Age Group: Adults Only
Min Karnofsky Score: Not Specified
Conditions: Newly Diagnosed: N
Recurrent: Y
Prior Surgery is Allowed
Prior Radiation is Allowed
Prior Chemotherapy is Allowed
Last Updated: 10/09/2008
Tumor Types: Anaplastic Astrocytoma
Any Malignant Brain Tumor
Glioblastoma Multiforme
Gliosarcoma
Comments: Taxol is a drug that is effective for many cancers including breast and lung to name two. It works very well at killing brain tumor cells in a dish, but lacks the ability to get across the blood brain barrier to work effectively in patients. This study utilizes a 15 amnio acid peptide which is a ligand for a receptor that actively transports across the blood brain barrier, as well as into certain tumor cells like glioblastoma. The peptide has three molecules of taxol conjugated.
Treatment Type: Chemotherapy.
Contact: Dana-Farber/Harvard Cancer Center
Clinical Trials Office - Dana-Farber/Harvard Cancer Center
Dana Farber Cancer Institute
Boston, MA 02115
Phone:617-582-8480
Email not available
Columbia University Medical Center
Steven Rosenfeld, MD
Contact: Mary Ann Kral
New York, NY 10032
Phone:212-305-7266
Click here to send an email
MD Anderson Cancer Center
Morris Groves, MD
Contact: Teresa Hanna
1400 Holcombe Blvd
Houston, TX 77030
Phone:713-563-1603
Click here to send an email
Website: www.mdanderson.org/diseases/braincancer/
University of Virginia Health System
David Schiff, MD
Co-Director, Division of Neuro-Oncology
Department of Neurology
Box 800432
Charlottesville, VA 22908-0432
Phone:434-982-4415
Fax: 434-982-4467
Click here to send an email
Website: www.uvabraintumor.com



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