Details For Selected Brain Tumor Treatment
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  • ID is our internal ID - starting with VT.
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Treatment Name: A Phase I dose escalation trial of Temodar that will attempt to determine the maximum tolerated dose of Temodar (Temozolomide) when given by prolonged oral exposure to children with recurrent or progressive brain tumors.
Keywords: Temodar
Phase: Phase 1
Treatment ID#s: VT616        
Age Group: Pediatric Only
Min Karnofsky Score: Not Specified
Conditions: Newly Diagnosed: N
Recurrent: Y
Prior Surgery is Allowed
Prior Radiation is Allowed
Prior Chemotherapy is Sometimes Allowed
Last Updated: 12/03/2005
Tumor Types: Anaplastic Astrocytoma
Brainstem Glioma
Craniopharyngioma
Ependyoma
Ganglioglioma
Glioblastoma Multiforme
Gliosarcoma
Low Grade Glioma
Medulloblastoma
Meningioma
Mixed Glioma
Oligodendroglioma High Grade
Oligodendroglioma Low Grade
Optic Glioma
PNET Tumor
Comments: Patients will receive Temodar for 42 consecutive days followed by a 28 day rest. Eligible patients must be no greater than 18 years of age at the time of study entry. Subsequent courses are permissible once a patient has completed 42 days of therapy followed by 28 days of rest. Each patient may continue to receive Temodar for up to 12 courses or until disease progression.
Treatment Type: Chemotherapy.
Contact: NYU Medical Center
Jeffrey Allen, MD
317 E. 34th Street, 10th Floor
New York, NY 10016
Phone:212-263-6725
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