Details For Selected Brain Tumor Treatment

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Last updated refers to the date when our listing for each treatment was last updated.
ID is our internal ID - starting with VT.
Min Karnofsky is a general guide to how well you have to function to use this treatment
For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.

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		Treatment Name:		Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

		Keywords:		Temodar

		Phase:		Phase 2

		Treatment ID#s:		VT867 NCT00005812

		Age Group:		Adults Only

		Min Karnofsky Score:		50: Requires considerable assistance and frequent medical care

		Conditions:		Newly Diagnosed: ? Recurrent: ? Prior Surgery is Allowed Prior Radiation is Sometimes Allowed Prior Chemotherapy is Sometimes Allowed meningeal gliomatosis

		Last Updated:		11/26/2005

		Tumor Types:		Lymphomas


		Comments:		Recent clinical trials demonstrating the activity of temozolomide against malignant gliomas make this agent a potentially useful treatment of both parenchymal and leptomeningeal tumors. Furthermore, animal studies have shown that between 41-44% of the serum drug concentration is achieved in the cerebrospinal fluid. Among other known active systemic agents for malignant glioma, only procarbazine achieves adequate CSF concentrations, but temozolomide offers the advantage of oral administration.

		Treatment Type:		Chemotherapy.

		Contact:		Norris Cotton Cancer Center, Thomas H. Davis, MD Lebanon, NH 03756 Phone: Email not available

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