Clinical Trial Details
Braintumor Website

[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT00598351 : Natural History Study of Patients With Neurofibromatosis Type 2
AgesMin: 8 Years Max: 75 Years

- All patients will have the clinical diagnosis of NF2 by established clinical criteria
or genetic testing.

- Males and females between the ages of 8 and 75.

- Capacity to undergo serial MRI scanning of the CNS.


- Clinically unstable condition that precludes serial clinical and imaging evaluation
(i.e. Class 3 congestive heart failure, severe chronic renal insufficiency, severe
chronic obstructive pulmonary disease).

- Allergy or relative contraindications to MRI contrast agents.

- Contraindication to MRI scanning such as surgery that involves metal clips or wires,
which might be expected to cause tissue damage or produce image artifacts.

- Patients with severe chronic renal insufficiency (glomerular filtration rate less
than 30 mL/min/1.73 m2), hepatorenal syndrome or post-liver transplantation.

- Patients who are pregnant at time of intake visit.
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