Clinical Trial Details
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NCT00805103 : Perfexion Brain Metastasis
PhasePhase 1
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- 1-5 recurrent brain metastases after WBRT, and

- At least 1 lesions >2cm in maximum diameter

- ECOG 0-2

- Life expectancy >3months

- Age ? 18 years old

Exclusion Criteria:

- Edentulous patients

- Prior surgery or injury to hard palate

- Severe claustrophobia

- Contraindication to MRI

- Contraindication to IV contrast (Gadolinium) administration

- Other medical conditions that would preclude study investigations

- Prior radiosurgery to recurrent lesions

- Radiation cannot be delivered at the assigned dose level in a manner that respects
OAR constraints ( (e.g. lesions within brainstem or abutting optic

- Any lesion >5cm in diameter, or total volume of tumor > 60cc

- Pregnant Women

- Men or women of childbearing potential who are unwilling to employ adequate
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