Clinical Trial Details
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NCT00897286 : Study of Stored Tumor Samples in Young Patients With Brain Tumors
AgesMin: N/A Max: 21 Years
Inclusion Criteria

- ATRT, CPC, medulloblastoma/PNET, ependymoma or glioma of the CNS as documented by the
local neuropathologist. Tumor may be primary, progressive or recurrent CNS tumor
including brain and/or spine. For fresh tissue, in some cases we must process the
tissue before a final diagnosis is available. If a xenograft is established from a
brain tumor that is later diagnosed to be a different histological subtype, we will
store frozen viable cells for potential future use. Although rare, patients with ATRT
may present with a primary renal and CNS tumor. In these instances samples will be
collected from both the kidney and CNS tumor for analysis if available.

- Tumor may be collected at surgery prior to histologic confirmation

- Age not more than 21 years at the time of initial diagnosis.

- Enrollment in the current version of the institution's banking protocol

- Biological parent(s) of participant (child) whose tumor is studied on this protocol.
These parents will be assigned to cohort P. The exclusion criteria below do not apply
to this cohort.

Exclusion Criteria

- Diagnosis of tumor outside the central nervous system.

- Age greater than 21 years at the time of diagnosis
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