Clinical Trial Details
Braintumor Website

[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT00945126 : Allogeneic Stem Cell Transplantation in Pediatric Patients With Malignant and Non-malignant High-risk Diseases
PhasePhase 2
AgesMin: N/A Max: 30 Years
Inclusion Criteria:

- Patients aged 0 to 30 years

- Written informed consent from patient and/or parents or guardian

- Patients with Karnofsky Index > 60%

- Malignant disease:

- acute lymphoblastic leukemia

- acute myeloid leukemia

- myelodysplastic syndrome

- chronic myeloid leukemia according to the standard indications

- solid tumors (e.g. neuroblastoma recurrence, soft-tissue sarcoma, Ewing's
sarcoma, osteosarcoma, hepatoblastoma)

. Non malignant disease:

- acquired anemias (e.g. severe aplastic anemia, particularly severe Evans

- congenital anemias (e.g. thalassemia and sickle cell anemia)

- Women reliable contraception method when appropriate

Exclusion Criteria:

- Participation in other clinical trials

- Patients, parents, or guardians unable to understand the nature, the importance and
the implications of the procedure

- Pregnant or nursing women

- Patients who underwent a stem cell transplantation in the last 250 days

- Patients with kidney, heart or liver insufficiency
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