Clinical Trial Details
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NCT01464177 : Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme
PhasePhase 2
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- 18 years of age or older

- KPS equal or greater than 60

- Anatomopathological confirmation of GBM

- Previous RT with therapeutic doses

- At least 5 months from the end of RT course

- Not a candidate to surgical resection

- Patients with partial resection after resection of recurrent GBM will be allowed

- Patients with local progression after resection of recurrent GBM will be allowed

- Lesion with a maximal 150cc volume, as defined by enhancing portion in contrast
enhanced MRI

- Hemoglobin levels (Hb) equal or greater than 10ng/dl. Blood transfusions to correct
the Hb will be allowed.

Exclusion Criteria:

- Important comorbidities

- Concomitant chemotherapy

- Contraindication to MRI

- Brainstem glioma
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