Clinical Trial Details
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NCT01516983 : Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation
PhasePhase 1/Phase 2
AgesMin: 18 Years Max: 75 Years
Inclusion Criteria:

- Histological or cytological confirmation of non-small cell lung cancer (NSCLC).

- Diagnosis of brain metastases on a Gadolinium-enhanced MRI. More than 3 sites of
intracranial metastases, or the longest diameter of the intracranial lesion is more
than 3cm.

- Positive EGFR mutation.

Exclusion Criteria:

- Previous usage of EGFR-TKI or antibody to EGFR: gefitinib, erlotinib, herceptin,

- CSF or MRI findings consistent with metastases of spinal cord, meninges or meningeal.
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