Clinical Trial Details
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NCT01653834 : Lymphocyte Reinfusion
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- • Age?18 year

- New diagnosed high grade glioma

- Post-operative treatment with standard RT/TMZ

- Karnofsky performance status ? 60%

- Normal bone marrow function with Hematocrit ? 30%, platelet ? 100K, ANC ? 1000,
and absolute lymphocyte count ? 1000 prior entry to this study. Blood product
transfusions are allowed.

Exclusion Criteria:

- Prior radiation therapy, chemotherapy, immunotherapy or therapy with biologic agents
or hormonal therapy for their brain tumor are excluded. Glucocorticoid therapy is

- Fresh CNS bleed, current anticoagulation use; and anti-VEGF therapy in past 6 weeks
are excluded.

- Patients must not have taken an ACE inhibitor within last 24 hours prior to
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