Clinical Trial Details
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[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT01811381 : Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease
PhasePhase 2
AgesMin: 50 Years Max: 90 Years
Inclusion Criteria:

- age between 50 and 90 years;

- Mini-Mental Status Exam (MMSE) scores greater than 24;

- subjective cognitive complaints based on subjective cognitive impairment questionaire
(Gifford et al. 2015) including non-amnestic or amnestic cognitive deficits MCI
(performance 1.5 standard deviation (SD) below normative means on The Consortium to
Establish a Registry for Alzheimer's Disease (CERAD) word list learning test);

- essentially intact activities of daily living (FAQ scores < 6);

- Sedentary (exercise < 30 minutes a day, 3 times a week);

- ambulatory, able exercise safely without cardiovascular symptoms, and able to pass a
graded treadmill test modified for the elderly;

- able to arrange transportation to the study;

- Willing and intellectually able to understand and to sign an informed consent and to
adhere to protocol requirements;

- community dwelling; and

- fluent in written and spoken English

- must screen positive for a Modified abbreviated MCI or SCD screen on phone, before
coming in to clinic for extensive testing

Exclusion Criteria:

- diagnosis of dementia,

- concurrent substance abuse disorder,

- psychosis or mood disorder,

- neurological disease affecting motor or cognitive abilities (e.g. Parkinson's
disease),or other significant uncontrolled medical problems,

- cannot get up and down from floor

- initiation of any new medications/treatment for cognitive impairment (i.e.
cholinesterase inhibitor, memantine) < 6 months prior to study enrollment
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