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|NCT01985750 : Understanding the Importance of Plasticity in the Brain Mechanisms of Dyspnoea Perception|
|Ages||Min: 45 Years Max: 85 Years|
- Males and females with chronic lung disease, aged between 45 and 85 years old who
have been referred for pulmonary rehabilitation.
- The subject is able and willing to give fully informed consent.
Any of the commonly accepted contraindications to MRI scanning, for example, severe
claustrophobia, presence of metallic implants, a pacemaker etc.
- Pregnancy. The risk to foetus of radiofrequency energy of the MRI scan is unknown.
- Inadequate understanding of verbal and written information in English, sufficient to
complete an MRI safety screening.
- Unable to lie flat and still for 1/2 hour
- Requirements for oxygen therapy
- Significant cardiac, neurological, psychiatric or metabolic disease
- Contra-indications to d-cycloserine: Alcoholism, known hypersensitivity, severe renal
- Regular therapy with prescribed opioid analgesics
- Antidepressant therapy (this may alter hippocampal plasticity)
- Previous pulmonary rehabilitation (because the learning may be different on repeat
pulmonary rehabilitation treatments)
|Links||Permanent Link to THIS page: https://virtualtrials.com/nct/display1trial.cfm?nct=NCT01985750
| Link to official Clinicaltrials.gov listing