Clinical Trial Details
Braintumor Website

[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02022293 : Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis
PhasePhase 2
AgesMin: 40 Years Max: 65 Years
Inclusion Criteria:

- Patients must have received radiation therapy for histologically confirmed
nasopharyngeal carcinoma.

- Prior irradiation <3 years prior to study entry.

- Male or fertile women who are willing to take contraception during the trial.

- Age 40-65 years old.

- Carotid stenosis < 50%.

- LDL-C between 100mg/dL?2.5mmol/L?and 190mg/dL?4.9mmol/L?.

- Ability to understand and the willingness to sign a written informed consent

Exclusion Criteria:

- History of bleeding related to tumor or radiotherapy during or after radiation.

- Evidence of tumor invasion to major vessels(for example the carotid artery).

- Severe complications, such as history of stroke, myocardial infarction, liver
diseases, thyroid dysfunction, inadequately controlled hypertension and epilepsy.

- Familial hypercholesterolemia.

- Taking lipid-lowing drugs.

- Aspartate aminotransferase(AST) or alanine aminotransferase(ALT) >upper limits of
normal (ULN), creatinine >ULN.

- Allergic history of atorvastatin.
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