Clinical Trial Details
Braintumor Website

[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02246491 : Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia
AgesMin: 3 Years Max: 100 Years
Inclusion Criteria:

Patients that meet the classic diagnosis of A-T and for whom the underlying mutation(s) is
known. The diagnosis of A-T has been made by the clinician using the following criteria:

1. Characteristic neurological abnormalities, including but not limited to oculomotor
apraxia, bulbar dysfunction, postural instability, and ataxia.

2. Presence of telangiectasia on the conjunctivae and/or skin.

3. Laboratory abnormalities including but not limited to elevated serum alpha-feto-
protein, level, absence of ATM on western blot, increased x-ray induced chromosomal
breakage in comparison to a control population, mutations in both alleles of the ATM
gene. Parents of the patients above, who are haploinsufficient and whose mutation is

Exclusion Criteria:

Patients under 2 years of age No subjects will be excluded on the basis of age, sex, race,
or socio-economic status.
LinksPermanent Link to THIS page:      |      Link to official listing

Home | Brain Tumor Guide | FAQs | Find A Treatment
Noteworthy Treatments | News | Virtual Trial | Videos | Novocure Optune® | Newsletter
Donations | Brain Tumor Centers | Survivor Stories | Temodar®
Fundraising For Research | Unsubscribe | Contact Us

Copyright (c) 1993 - 2020 by:
The Musella Foundation For Brain Tumor Research & Information, Inc
1100 Peninsula Blvd
Hewlett, NY 11557