Clinical Trial Details
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NCT02248233 : Nimodipine for Treating Acute Massive Cerebral Infarction
PhasePhase 4
AgesMin: 18 Years Max: 80 Years
Inclusion Criteria:

- First onset at age ? 80 years, no other severe medical complications;

- Clear consciousness or mild disturbance of consciousness; paralysis of upper and
lower extremities on one side with grade 0-3 muscle strength in paralyzed limbs;

- CT reveals early massive cerebral infarction (without cerebral hemorrhage or old

- Blood pressure within, or higher than, the normal range.

Exclusion Criteria:

- Clinical manifestations are noticeably improved before treatment;

- Disorders of consciousness, manifesting as severe lethargy or coma;

- Mild neurological deficits, such as pure sensory disturbances, ataxia, dysarthria,
and hemiparesis;

- Severe hypotension (systolic pressure < 90 mmHg, diastolic pressure < 60 mmHg);

- Heart rate < 60 BPM; sinus bradycardia;

- Severe heart, brain or kidney dysfunction, or malignant tumor.
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