Clinical Trial Details
Braintumor Website

[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02336282 : Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic Leukemia
PhasePhase 2
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- Current St. Jude LIFE (SJLIFE) Protocol Participant

- Long term survivor of acute lymphoblastic leukemia (ALL)

- Currently ? 18 years of age

- Wi-Fi internet access at home

- History of executive dysfunction, documented by neurocognitive testing, and defined
as having an age-adjusted standard score <10th percentile on Trail Making Test Part
B, Verbal Fluency, or Digit Span Backward.

- History of self-reported executive dysfunction in daily life, defined as having a
standardized score <10th percentile on BRIEF Initiate, Shift, or Working Memory
domains OR having scored <10th percentile on the Childhood Cancer Survivor Study
Neurocognitive Questionnaire Task Efficiency of Memory domains.

- Participant is able to speak and understand the English language.

Exclusion Criteria:

- Any survivor with full scale intelligence quotient (IQ) <80

- Currently on stimulants or other medications intended to treat cognitive impairment

- History of seizures

- No implanted medical devices or implanted metal in the head

- Currently pregnant or planning to become pregnant.

- Inability or unwillingness of research participant or legal guardian/representative
to give written informed consent.
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