Clinical Trial Details
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[Information provided by: ClinicalTrials.gov, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02387840 : Feasibility and Clinically Application of Magnetic Resonance Fingerprinting
PhaseN/A
AgesMin: N/A Max: 35 Years
Eligibility
Inclusion Criteria:

- Subjects undergoing MRI evaluation of the brain

- NF1 status will be determined by clinical exam or genetic testing

- NF1-associated Optic Pathway Glioma (OPG) will be defined as radiographic evidence of
glioma along the optic nerve, chiasm, tract or radiation in a child with NF1

- Untreated low grade gliomas will be imaging-defined gliomas that have not yet been
exposed to radiation or systemic chemotherapy. Those exposed to therapy will have had
radiation and/or systemic chemotherapy more than 1 month prior to scans

Exclusion Criteria:

- History of mental retardation unrelated to brain tumor

- Presence of a genetic disorder other than NF1 that effects cognition or is associated
with MR imaging abnormalities (e.g. tuberous sclerosis)

- History of cerebrovascular accident (stroke)

- Birth weight below five pounds, premature birth prior to 36 weeks of gestation, or
ischemic episode at birth

- Major psychiatric diagnosis prior to neuro-oncological diagnosis
LinksPermanent Link to THIS page: https://virtualtrials.com/nct/display1trial.cfm?nct=NCT02387840      |      Link to official Clinicaltrials.gov listing
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