Clinical Trial Details
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[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02672033 : Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma
PhasePhase 0
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- Histologically confirmed epithelioid predominantly (> 70%) subtype malignant pleural

- Patient must have been evaluated by a University of California Los Angeles (UCLA)
thoracic surgeon, and deemed medically and technically suitable for a
pleurectomy/decortication procedure

- Karnofsky performance status (KPS) >= 70 or Eastern Cooperative Oncology Group (ECOG)

- If a woman is of childbearing potential, a negative urine or serum pregnancy test
must be documented; women of childbearing potential must agree to use adequate
contraception (hormonal or barrier method of birth control; or abstinence) for
duration of study participation and for up to 4 weeks following the study

Exclusion Criteria:

- Patients who have previously received therapeutic radiation therapy to the chest

- Active systemic, pulmonary, or pericardial infection

- Use of chemotherapy within 4 weeks of the planned start of radiation therapy

- Pregnant women, or women of childbearing potential who are sexually active and not
willing/able to use medically acceptable forms of contraception for the entire study
period and for up to 4 weeks after the study

- Refusal to sign the informed consent

- Patients who are participating in a concurrent treatment protocol
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