Clinical Trial Details
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NCT02731521 : Clinical Development of MR Spectroscopy and Imaging in Brain Cancers
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

(120 Brain Tumor Patients)

- All races and ethnicities

- Must meet at least one of the 3 following criteria regarding diagnosis:

- Histological diagnosis of a brain tumor

- Pre-operative MR imaging suggestive of a brain tumor

- Radiographic diagnosis of brain tumor in an inoperable location (e.g. brainstem)

- Pretreatment evaluations required for eligibility include a medical history, physical
examination, and neurological exam within 30 days prior to study entry.

- Patient must be able to provide study-specific consent prior to study entry and Health
Insurance Portability and Accountability Act of 1996 (HIPAA) authorization.

- Karnofsky performance status >70%

- Life expectancy greater than 3 months.

(50 Non-Tumor Neurological Disorders)

- All races and ethnicities

- Patients with clinically-proven multiple sclerosis, temporal lobe epilepsy, stroke, or

(5 Health Volunteers)

- 18-40 years of age

- All races and ethnicities

- Excellent general health

Exclusion Criteria:

- Under age 18

- Cardiac pacemaker

- Intracranial clips, metal implants, or external clips within 50 cm from the head

- Metal in eye

- Pregnancy

- Claustrophobia

- Obesity or any other factors that provide difficulty with supine pose in the magnet

- Patients who are unable to provide informed consent

- Patients who are pregnant or nursing

- Patients with severe kidney dysfunction or uncontrolled cardiac dysfunction

- Patients who are claustrophobic or have other contraindication to MRI, such as
implanted pacemaker device, vascular clips, surgical clips, prosthetic valves,
pace¬makers, otologic implants

- Patients with uncontrolled psychiatric manifestations of their brain tumor

- Patients for 7 Tesla scans can have no metal in the body
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