Clinical Trial Details
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NCT02793921 : Exercise Program in Cancer and Cognition
AgesMin: 51 Years Max: 75 Years
Inclusion Criteria:

1. Postmenopausal female

2. Maximum age 75 years

3. Able to speak and read English

4. Minimum completion of 8 years of education

5. Diagnosed with Stage 0, 1, 2 or 3a Breast Cancer

6. Eligible to receive aromatase inhibitor therapy

7. At least two weeks post-breast conserving surgery or three weeks post-breast
conserving surgery with sentinel lymph node biopsy or four weeks post-mastectomy

8. Medical clearance by their breast cancer surgeon

Exclusion Criteria:

1. Prior diagnoses of cancer (exception with some skin cancers)

2. Clinical evidence of distant metastases

3. Self-report of hospitalization for psychiatric illness within the last two years

4. History of neurologic illness

5. Any breast cancer surgery complications including persistent seroma requiring
aspiration, wound dehiscence, infection, prolonged drain output, lymphedema
(confirmed by participant's surgical oncologist)

6. Reconstructive surgery

7. A medical condition that would preclude them from exercising including a history of
coronary artery or pulmonary disease, congestive heart failure, angina, uncontrolled
arrhythmia, or other symptoms that indicate increased risk for an acute
cardiovascular event

8. Current treatment for Type II Diabetes

9. Eating disorders or a history of substance abuse

10. Any use of an assisted walking device

11. Recent history of falls or balance problems

12. Current beta-blocker use

Additional Exclusion Criteria for Neuroimaging subgroup:

1. Presence of metal implants (i.e., pacemaker, some stents)
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