Clinical Trial Details
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NCT02811250 : Stereotactic Radiotherapy for Renal Cancers
PhasePhase 1
AgesMin: 75 Years Max: N/A
Inclusion Criteria:

- Patient aged over 75 years with an operable renal tumor or patient with inoperable
renal tumor irrespective of age, or patient with metastatic renal tumor and
indication for nephrectomy.

- Histologically-confirmed Renal carcinoma less than or equal to 4 cm

- Tumor that is visible and measureable on abdominal scanner and/or MRI (Magnetic
Resonance Imaging)

- Karnofsky performance status ? 60%

Exclusion Criteria:

- Patient with only one kidney and renal cancer

- Patient not able to cooperate during treatment

- Previous history of abdominal radiation therapy

- Tumor having infiltrated the renal pelvis

- Polycystic kidney disease

- Previous history of intestinal inflammatory disease such as ulcerative colitis or
Crohn's disease

- Renal insufficiency (creatinine clearance <30 ml/mm evaluated by DTPA
(diethylenetriamine pentaacetic acid ) scintigraphy)

- Uncontrolled hypertension (SBP(systolic blood pressure) above 160 mmHg DBP(diastolic
blood pressure) above 100 mmHg with antihypertensive treatment)

- Non primary lesions (benign lesions such as angiomyolipoma, renal metastases,…)

- Antineoplastic and/or antiangiogenic treatment in the month preceding radiotherapy

- Progressive cancer other than renal cancer at time of inclusion with the exception of
in situ cervical carcinomas, basal cell carcinoma of the skin, and non-metastatic
prostate cancer controlled without hormone therapy

- Participation in another ongoing study that may interfere with the present study
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