Clinical Trial Details
Braintumor Website

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NCT02840123 : Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines
PhasePhase 1
AgesMin: 3 Years Max: 18 Years
Inclusion Criteria:

- Newly diagnosed DIPG Patients without progressive disease

- Aged between 3 and 18 yo Lansky scale >50 (Karnofsky for patients aged more than 16

- Life expectancy > 8 weeks

- Preserved bone marrow function Normal hepatic and renal function

Exclusion Criteria:

- Impossibility to perform aphaeresis

- Patient participation of other experimental study within the last 3 months

- Patient under antitumor treatment in the last 4 weeks

- Co-morbidity that does not allow the study treatment

- Patients requiring > 2mg/day of dexamethasone treatment Corticoid-dependent patients

- Patients under uncontrolled infection

- Positive serologies of HIV, hepatitis C virus (HCV) or hepatitis B virus (HBV)
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