Clinical Trial Details
Braintumor Website

[Information provided by:, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02903680 : RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED
PhasePhase 1
AgesMin: 8 Years Max: 18 Years
Inclusion Criteria:

- presenting a diagnosis of acute migraine

- requiring treatment with an intravenous rescue therapy (either metoclopramide or
prochlorperazine) because of the severity of the migraine according to the treating

Exclusion Criteria:

- known allergy to any study drugs or a component

- absolute contraindication to receiving corticosteroids such as: active untreated
infections, systemic fungal infections, cerebral malaria, respiratory tuberculosis,
hypertension, heart failure, renal or hepatic impairment, GI diseases, myasthenia
gravis, diabetes, cataracts, glaucoma, seizure disorder, thyroid dysfunction, and
thromboembolic tendencies

- patients who were already on corticosteroids

- patients who were initially recruited but who did not respond to the abortive
migraine therapy (no modification in the pain level) were not randomized to receive
the intervention or placebo.
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