Clinical Trial Details
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NCT02989285 : Identification and Quantification of HIV CNS Latency Biomarkers
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- HIV-infected

- Aged >18 years

- On HAART with viral load suppression (<50 copies / ml) in both plasma and CSF for at
least 6 months

- Able to provide informed consent

Exclusion Criteria:

- Non-HIV related neurological disorder or active CNS opportunistic infection as
assessed by full blood count, electrolytes, creatinine, glucose, liver function
tests, venereal disease reaction level (VDRL), MRI brain scan and CSF analyses for
cell count, protein, glucose, culture, VDRL and cryptococcal antigen

- Psychiatric disorders on the psychotic axis, current major depression, current
substance use disorder and/or 12 month history of severe substance use disorder

- Active Hepatitis C co-infection

- History of severe traumatic brain injury (post-traumatic amnesia (PTA) duration>1
day) or loss of consciousness > 30 minutes from other cause (e.g., hypoxic brain

- Non-proficient in English
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