Clinical Trial Details
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NCT03179449 : In Vivo Characterization of Macrophages in Pediatric Patients With Malignant Brain Tumors Using Ferumoxytol-enhanced MRI
PhaseEarly Phase 1
AgesMin: 2 Years Max: N/A
Inclusion Criteria:

- Any patient with suspected malignant brain tumor on diagnostic MR imaging who will
undergo a resection

Exclusion Criteria:

- Informed consent cannot be obtained either from the patient or legal representative

- Severe coexisting or terminal systemic disease that may interfere with the conduct of
the study

- Contraindication to MRI (metal implants)

- Hemosiderosis/hemochromatosis

- Iron overload from any cause (not just hemosiderosis or hemochromatosis), even if
secondary to frequent blood transfusions, severe chronic hemolysis, excess dietary or
parenteral iron, or any other etiology

- Known hypersensitivity to ferumoxytol or any of its components

- Pregnant patients
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