Clinical Trial Details
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NCT03254381 : The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
AgesMin: 60 Years Max: 80 Years
Inclusion Criteria:

1) be community-dwelling 2) be aged 60-80 years 3) be "at-risk" for diabetes, where they
have one of the following: i) blood glucose level of 6.1-7 mmol/L, ii) BMI > 25, or iii)
score > 21 on the CANRISK diabetes questionnaire 4) score > 24/30 on MMSE 5) score > 6/8 on
Lawton and Brody's Independent Activities of Daily Living (IADL) scale 6) have visual
acuity of at least 20/40, with or without corrective lenses 7) speak and understand English
fluently 8) complete the Physical Activity Readiness Questionnaire (PAR-Q) 9) obtain
physician's clearance to start a supervised exercise program

Exclusion Criteria:

1) have a current medical condition for which exercise is contraindicated 2) have
participated regularly in resistance or aerobic training in the last 6 months 3) have been
diagnosed with neurodegenerative disease (including dementia, Alzheimer's disease, or
Parkinson's disease) 4) have experienced a vascular incident (e.g., stroke, myocardial
infarction) 5) have been diagnosed with a psychiatric condition 6) have untreated
depression 7) are currently on hormone replacement therapy 8) have clinically significant
peripheral neuropathy or severe musculoskeletal or joint disease 9) are currently taking
psychotropic medications 10) are unable to participate in MRI (have metal or electronic
implants, or are claustrophobic)
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