Clinical Trial Details
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NCT03285932 : Stereotactic Radiotherapy of the Resection Cavity of Brain Metastases vs. Post-operative Whole-brain Radiotherapy
PhasePhase 2
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- histologically confirmed solid cancer

- MRI confirmed cerebral metastases

- Neurosurgical resection of one cerebral metastasis

- age = 18 years of age

- Karnofsky Performance Score >60

- for women with childbearing potential, (and men) adequate contraception.

- ability to understand character and individual consequences of the clinical trial

- written informed consent (must be available before enrolment in the trial)

Exclusion Criteria:

- refusal of the patients to take part in the study

- previous radiotherapy to the brain

- > 10 unresected brain metastases in postoperative MRI

- Patients who have not yet recovered from acute toxicities of prior therapies

- known carcinoma < 2 years ago (excluding carcinoma in situ of the cervix, basal cell
carcinoma, squamous cell carcinoma of the skin) requiring immediate treatment
interfering with study therapy

- pregnant or lactating women
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