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|NCT03302026 : Real Time fMRI and Quitting Smoking|
|Ages||Min: 18 Years Max: 65 Years|
1. Treatment-seeking smokers between the ages of 18 and 65, reporting consumption of at
least 10 cigarettes per day for at least the past 6 months;
2. Planning to live in the area for at least the next month;
3. Capable of giving written informed consent, which includes compliance with the
requirements and restrictions listed in the combined consent and HIPAA form;
4. Able to communicate fluently in English (speaking, writing, and reading).
1. Use of chewing tobacco or snuff or cigars;
2. Current enrollment or plans to enroll in another smoking cessation program or research
study in the next month;
3. Current or anticipated (within the next month) use of smoking cessation medications or
nicotine replacement therapy (NRT);
4. A baseline carbon monoxide (CO) reading less than 10ppm.
1. Current alcohol consumption that exceeds 25 standard drinks/week;
2. Positive breath alcohol concentration test (BrAC greater than or equal to 0.01) at
intake; a. Participants testing positive for breath alcohol with a reading equal to or
greater than .08 (the legal driving limit) or who are visibly impaired will be
instructed not to drive themselves home after the appointment. If a participant needs
to use a phone to call for a safe ride home, an office telephone will be made
available to the participant.
Current use or recent discontinuation (within the past 30 days at the time of Intake) of:
1. Smoking cessation medication (e.g., Zyban, Wellbutrin, Wellbutrin SR, Chantix, NRT);
2. Anti-psychotic medications;
3. Any medication that could compromise participant safety as determined by the Principal
Investigator and/or Study Physician;
Daily use of:
4. Opiate-containing medications for chronic pain.
1. Women who are pregnant, planning a pregnancy, and/or breast feeding. All female
subjects of childbearing potential will undergo a urine pregnancy test at Intake and
at each scan session.
2. History of epilepsy or a seizure disorder;
3. History of stroke;
4. Self-reported brain (or CNS) or spinal tumor;
5. Self-reported history of head trauma;
6. Self-reported history or current diagnosis of psychosis.
1. Self-reported use of pacemakers, certain metallic implants, or presence of metal in
the eye as contraindicated for fMRI;
2. Self-reported history of claustrophobia;
3. Being left-handed;
4. Color blindness;
5. Weight greater than 250lbs at intake;
6. Self-reported history of gunshot wounds;
7. Any impairment preventing participants from using the response pad necessary for the
8. Circumstances or conditions that may interfere with magnetic resonance imaging (MRI).
1. Any medical condition, illness, disorder, or concomitant medication that could
compromise participant safety or treatment, as determined by the Principal
2. Enrollment or plans to enroll in another research study;
3. Inability to provide informed consent or complete any of the study tasks as determined
by the Principal Investigator.
|Links||Permanent Link to THIS page: https://virtualtrials.com/nct/display1trial.cfm?nct=NCT03302026
| Link to official Clinicaltrials.gov listing