Clinical Trial Details
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NCT03476070 : Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)
AgesMin: 15 Years Max: 39 Years
Inclusion Criteria:

- between 15-39 years of age

- newly diagnosed with breast cancer, lymphoma or germ cell tumor with treatment intent
determined as curative by medical oncologist

- scheduled for chemotherapy with or without non-cranial radiotherapy

- no prior history of chemotherapy and/or radiotherapy

- able to read and understand English

- capable of giving informed consent (or obtaining parents' consent if required)

Exclusion Criteria:

- physically or mentally incapable of providing verbal/written consent

- diagnosed with primary or metastatic brain tumor(s) or relapsed disease

- treatment includes intrathecal or intraventricular chemotherapy

- evidence of psychosis or underlying neuropsychiatric illness that may impair cognitive

- have immediate family member who is enrolled as in the healthy control arm

- any contraindication to MRI as stated in the study protocol including: pregnancy,
metal fragments/implants in body, known claustrophobia, and non-removable metal
orthodontic braces, metallic retainers and oral wires
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