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  • Question: My 11-year-old son was diagnosed with metastatic medulloblastoma in April, 2003. He underwent surgery and Head Start II protocol (high dose chemotherapy with stem cell rescue) and then underwent 6 weeks of radiation to the posterior fosse and spine. In November, 2005, another tumor was discovered on the frontal lobe. It was removed. Six weeks of radiation was done to the frontal lobe. Chemotherapy was started: oral Temodar, IV vincristine and oral CCNU. In April, 2007, while still on chemotherapy, another tumor was found on the ventricle. Surgery was done, an an Ommaya reservoir was placed, and he has been undergoing Topetecan since April. Our doctors are considering another stem cell rescue. Ethan has stem cells from the first collection in 2003. He would only undergo the 3 days of high dose chemo to wipe out his immune system. Our only other option is to continue with Topetecan which he tolerates very well. Please advise on 2nd stem cell rescue and any studies you have read about or if this is done or not.
  • Answer:08/09/2007
    Dr. Jon Finlay at Childrens Hospital in Los Angeles has the most experience with tandem stem cell rescues in recurrent disease. I would call him.
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