Pediatric Brain Tumor Mutations are Detectable in Cerebrospinal Fluid
This is a huge advance, although it is a small study and needs to be validated. The concept of a liquid biopsy is that instead of trying to get tumor tissue directly, you get it from blood, or in this case, cerebral spinal fluid, which is a lot easier than brain surgery. You can usually only get a biopsy once or twice of the actual tumor. In some cases, it is dangerous to do a biopsy at all. However, with a liquid biopsy, you can repeat it over time, and see how the tumor is responding to treatment. We are funding the development of a new drug that targets the exact marker this researcher is testing for. I can envision a day when you do this test, and personalize treatment based on it. Then repeat to see how the tumor is trying to mutate around the drug and be able to change the treatment plan.
Posted on: 04/21/2017
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