Clinical Trials
Braintumor Website

 For People with Newly Diagnosed Glioblastoma Multiforme
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM)
With Epidermal Growth Factor Receptor (EGFR) Amplification

 For People with Reccurent Glioblastoma Multiforme (and other malignant gliomas)
A Study of ABT-414 in Adult or Pediatric Subjects With Recurrent Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Glioblastoma at First Recurrence or Progression
Aldoxorubicin Trial for recurrent GBM.

These trials were the most recently added or updated

NCT Trial Name# of CentersLast Updated

NCT03155620

  Pediatric MATCH: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders
2210/09/2017

NCT02974621

  Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent Glioblastoma
110/09/2017

NCT02971501

  Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases
410/09/2017

NCT03190967

  T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
110/07/2017

NCT03291977

  Interest of Fluorescein in Fluorescence-guided Resection of Gliomas (FLEGME)
110/06/2017

NCT03248544

  Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery
210/06/2017

NCT03242824

  The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma
310/06/2017

NCT03233204

  Pediatric MATCH: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes
1710/06/2017

NCT03220035

  Pediatric MATCH: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations
1810/06/2017

NCT03213704

  Pediatric MATCH: Trk Inhibitor LOXO-101 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions
1910/06/2017

NCT03213678

  Pediatric MATCH: PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations
1710/06/2017

NCT03213665

  Pediatric MATCH: Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations
1710/06/2017

NCT02780804

  Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
1910/06/2017

NCT01649830

  Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma
110/06/2017

NCT03174197

  Atezolizumab (aPDL1) + Temozolomide and Radiation for Newly Diagnosed Glioblastoma (GBM)
110/05/2017

NCT03030066

  Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas
110/05/2017

NCT02993146

  Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
510/05/2017

NCT02212574

  Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
1310/05/2017

NCT02177578

  Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
110/05/2017

NCT01466686

  Low Dose Radiation Therapy for Glioblastoma Multiforme
310/05/2017

NCT01445483

  Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases
110/05/2017

NCT01445288

  Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
110/05/2017

NCT00267865

  Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma
110/05/2017

NCT00083512

  Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme
110/05/2017

NCT00067821

  Comparison of PET and Proton MRS Imaging to Evaluate Pediatric Brain Tumor Activity
110/05/2017

NCT00009035

  Natural History of Patients With Brain and Spinal Cord Tumors
110/05/2017

NCT03137888

  Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma
110/04/2017

NCT02942264

  TG02 Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of TG02 Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
110/04/2017

NCT02820454

  Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles
110/04/2017

NCT02460874

  Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)
110/04/2017

NCT02137759

  MRSI to Predict Response to RT/TMZ ± Belinostat in GBM
210/04/2017

NCT01505569

  Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
110/04/2017

NCT02869243

  A Dose Escalation Phase I Study Of Human- Recombinant Bone Morphogenetic Protein 4 Administrated Via CED In GBM Patients
110/03/2017

NCT02667587

  An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
12010/03/2017

NCT02328300

  FLT PET/MR for Evaluation of Pseudoprogression in Patients With Brain Lesions
110/03/2017

NCT02095132

  WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
2110/03/2017

NCT01454596

  CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII
110/03/2017

NCT01266096

  PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study
110/03/2017

NCT00870129

  Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
110/03/2017

NCT00089245

  Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer
110/03/2017

NCT02900248

  CureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physician Choice
110/02/2017

NCT02880410

  Feasibility Study on LITT for Newly Diagnosed Glioblastoma
210/02/2017

NCT02831959

  Effect of TTFields (150 kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS)
4510/02/2017

NCT02392078

  Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
1410/02/2017

NCT02308020

  A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain
5010/02/2017

NCT03273712

  Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)
110/01/2017

NCT03150862

  A Study Assessing BGB-290 With Radiation and/or Temozolomide (TMZ) in Subjects With Newly Diagnosed or Recurrent Glioblastoma
509/29/2017

NCT03052738

  Medical Marijuana in the Pediatric Central Nervous System Tumor Population
109/29/2017

NCT03028337

  Single Versus Multifraction Salvage Spine Stereotactic Radiosurgery for Previously Irradiated Spinal Metastases
109/29/2017

NCT02960230

  H3.3K27M Peptide Vaccine for Children With Newly Diagnosed DIPG and Other Gliomas
809/29/2017



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