Clinical Trials
Braintumor Website

 For People with Newly Diagnosed Glioblastoma Multiforme
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM)
With Epidermal Growth Factor Receptor (EGFR) Amplification

 For People with Reccurent Glioblastoma Multiforme (and other malignant gliomas)
A Study of ABT-414 in Adult or Pediatric Subjects With Recurrent Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Glioblastoma at First Recurrence or Progression
Neuroblate MRI-Guided Laser Surgery for recurrent GBM.
Aldoxorubicin Trial for recurrent GBM.

These trials were the most recently added or updated

NCT Trial Name# of CentersLast Updated

NCT02780804

  Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
1703/08/2017

NCT02658279

  Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype
603/08/2017

NCT02133183

  Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma
403/08/2017

NCT02095132

  WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
1903/08/2017

NCT01445288

  Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
103/08/2017

NCT02858895

  Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Glioblastoma at First Recurrence or Progression
503/07/2017

NCT02462629

  Study of BLZ-100 in Pediatric Subjects With CNS Tumors
103/07/2017

NCT02375841

  Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and Caregivers
503/07/2017

NCT01326104

  Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor
303/07/2017

NCT00811148

  Florida Center for Brain Tumor Research
103/07/2017

NCT02697734

  Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease
1603/06/2017

NCT02359565

  Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, or Hypermutated Brain Tumors
103/06/2017

NCT02311920

  Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
1003/06/2017

NCT01922076

  WEE1 Inhibitor AZD1775 and Local Radiation Therapy in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
303/06/2017

NCT00887146

  Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
16903/06/2017

NCT01677741

  A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
1603/04/2017

NCT03065218

  Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer Patients
103/03/2017

NCT02914067

  Cognitive Biomarkers in Pediatric Brain Tumor Patients
103/03/2017

NCT02896335

  Palbociclib In Progressive Brain Metastases
103/03/2017

NCT02886585

  Pembrolizumab In Central Nervous System Metastases
203/03/2017

NCT02667587

  Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer).
11303/03/2017

NCT02617589

  Study of Nivolumab Compared to Temozolomide, Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
11603/03/2017

NCT02559752

  Computer-based Neurocognitive Assessment in Children With Central Nervous System Tumors Receiving Proton Beam Radiation Therapy
103/03/2017

NCT02490878

  Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases
1103/03/2017

NCT02423525

  Safety Study of Afatinib for Brain Cancer
103/03/2017

NCT02372409

  Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors
103/03/2017

NCT02308020

  A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain
5203/03/2017

NCT02335918

  A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors
1303/02/2017

NCT02120287

  Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme
103/02/2017

NCT01817751

  Sorafenib Tosylate, Valproic Acid, and Sildenafil Citrate in Treating Patients With Recurrent High-Grade Glioma
103/02/2017

NCT01724606

  Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)
603/02/2017

NCT01622868

  Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
10403/02/2017

NCT01621906

  18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain
603/02/2017

NCT01288235

  Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
103/02/2017

NCT03034135

  Safety, Tolerability and Efficacy of Disulfiram and Copper Gluconate in Recurrent Glioblastoma
103/01/2017

NCT02997423

  Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)
1203/01/2017

NCT02616393

  Study of Tesevatinib in Subjects With Non-Small Cell Lung Cancer, EGFR Activating Mutation, Prior Treatment With a Tyrosine Kinase Inhibitor, and Brain Metastases or Leptomeningeal Metastases
1003/01/2017

NCT02431572

  A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or Immunotherapy
203/01/2017

NCT01478321

  Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas
503/01/2017

NCT02886572

  SIMT Stereotactic Radiosurgery Outcomes Study
102/28/2017

NCT02844439

  Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma
1002/28/2017

NCT02607124

  A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy
102/28/2017

NCT02576431

  Study of LOXO-101 in Subjects With NTRK Fusion Positive Solid Tumors (NAVIGATE)
3302/28/2017

NCT01421524

  Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma
2702/28/2017

NCT02835599

  Registry for the EVolution Of LUng Cancer Therapy Implementation and Outcomes Now
702/27/2017

NCT02915744

  A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine
402/24/2017

NCT02568267

  Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
10802/24/2017

NCT02060383

  Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly
4202/24/2017

NCT01491893

  PVSRIPO for Recurrent Glioblastoma (GBM)
102/24/2017

NCT00001595

  An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
102/24/2017



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